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How Sepsis Affects the Body?

Sepsis is fairly common and highly treatable in mild stages. Sepsis occurs when a localized bacterial infection causes a systemic inflammatory reaction in the body. As a method of fighting the infection, the body releases cytokines and other mediators, proteins that help fight bacteria. These cytokines cause blood vessels to dilate, lowering blood pressure and causing systemic inflammation. Treated with antibiotics and possibly fluids (either orally or through IV), sepsis in may be mild and easy to cure. However, if left untreated or if the body does not respond properly to treatment, the inflammation may can causea dangerous drop in blood pressure or multi-organ failure by depriving the organ systems of the blood flow they need, a state known as septic shock. Once a patient reaches septic shock, mortality rates increase to 40-50%.

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