Sepsis and MRSA (methicillin-resistant Staphylococcus)  are different, although MRSA can lead to sepsis. MRSA is a very specific type of infection which may lead to sepsis. There are many other bacterial infections that may cause sepsis such as E. coli, Streptococcal infections, or Pneumococcal infections. Staphylococcus aureus is harbored in everyone’s nose and on the surface of the skin.

Some people have a particular type of Staph (for short) that is resistant to certain antibiotics is called MRSA (as it is resistant to methicillin). This particular type of Staph infection may be difficult to treat since it is resistant to some of our more common antibiotics. MRSA infections may occur when the bacteria Staphylococcus aureus enters the skin through a cut or other opening. When the bacteria enter the blood, one is said to have MRSA bacteremia, which may lead to MRSA sepsis.